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Mark A Harris Selected Research

chromium hexavalent ion

1/2020An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet.
10/2019Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway.
1/2018Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium.
12/2017Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium.
11/2017Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents.
1/2017Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats.
1/2017High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure.
12/2016Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.
4/2016Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium.
8/2015Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy.
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Mark A Harris Research Topics

Disease

22Neoplasms (Cancer)
01/2020 - 01/2011
11Hyperplasia
01/2020 - 09/2011
9Carcinogenesis
10/2019 - 09/2011
4Intestinal Neoplasms (Intestinal Cancer)
10/2019 - 05/2014
1Iron Deficiencies
03/2014
1Anemia
03/2014
1Carcinoma (Carcinomatosis)
03/2013
1Adenoma (Adenomas)
03/2013
1Inflammation (Inflammations)
01/2011

Drug/Important Bio-Agent (IBA)

23chromium hexavalent ionIBA
01/2020 - 01/2011
15Drinking WaterIBA
01/2018 - 01/2011
3CaptanIBA
01/2020 - 12/2017
3folpet (Phaltan)IBA
01/2020 - 12/2017
3CarcinogensIBA
10/2019 - 01/2011
3sodium bichromate (sodium dichromate)IBA
06/2013 - 01/2012
2DNA (Deoxyribonucleic Acid)IBA
01/2015 - 01/2011
1MetalsIBA
01/2020
1Hypoxia-Inducible Factor 1IBA
10/2019
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
10/2019
1Proteins (Proteins, Gene)FDA Link
01/2017
1DioxinsIBA
01/2014
1SoilIBA
01/2014
1GATIBA
06/2013
1Codon (Codons)IBA
06/2013
1IronIBA
01/2012
1CytokinesIBA
01/2012